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Image Search Results
Journal: Journal of immunology (Baltimore, Md. : 1950)
Article Title: CD74 deficiency mitigates systemic lupus erythematosus-like autoimmunity and pathological findings in mice
doi: 10.4049/jimmunol.1600028
Figure Lengend Snippet: CD74 expression and antigen presentation activity in Faslpr mice. A. Immunoblot detected CD74 expression, both the p41 full-length products and p10 processed fragments, in kidney extracts from 24-week-old WT and Faslpr mice. B. Immunostaining to detect CD74 (p41) expression in kidneys from 24-week-old WT mice. Scale: 50 μm. C. Immunostaining detected CD74 (p41) expression in kidneys from 24-week-old Faslpr mice. Scale: 200 μm and 50 μm, inset scale: 50 μm. D. CD74 (p41) expression in kidney TECs before and after stimulation with IL6 and IFN-γ. E. CD4+ T cell culture medium IL2 levels after activation with TECs from 24-week-old WT and Faslpr mice in the presence or absence of autoantigens as indicated. F. Mixed lymphocyte reactions of presenter splenocytes from 24-week-old FaslprCd74+/+ and FaslprCd74−/− mice and responder cells from bm12 mice. G. Autoantigen histone presentation assay. ELISA determined IL2 levels in splenocytes from 24-week-old FaslprCd74+/+ and FaslprCd74−/− mice treated with and without histone. Data in E–G are representative of three independent experiments.
Article Snippet: The ELISA kits used in this study include:
Techniques: Expressing, Immunopeptidomics, Activity Assay, Western Blot, Immunostaining, Cell Culture, Activation Assay, Enzyme-linked Immunosorbent Assay
Journal: Journal of immunology (Baltimore, Md. : 1950)
Article Title: CD74 deficiency mitigates systemic lupus erythematosus-like autoimmunity and pathological findings in mice
doi: 10.4049/jimmunol.1600028
Figure Lengend Snippet: CD74 deficiency mitigates SLE-like pathology in SLE-prone Faslpr mice. A. Kidney PAS staining and glomerulus and tubulointerstitial scores; B. Kidney IgG and C3 immunofluorescent staining and glomerulus scores. C. Kidney Mac-2, MCP-1, and MHC-II immunostaining. D. ELISA determined serum IL6, IL17A, IL2, and TGF-β levels from 24-week-old FaslprCd74+/+ and FaslprCd74−/− mice. The number of mice per group is indicated in each parenthesis. Representative graphs for A–C are shown to the left of each panel. Scale: 50 μm.
Article Snippet: The ELISA kits used in this study include:
Techniques: Staining, Immunostaining, Enzyme-linked Immunosorbent Assay
Journal: Journal of ethnopharmacology
Article Title: Antiviral effect of fufang yinhua jiedu (FFYH) granules against influenza A virus through regulating the inflammatory responses by TLR7/MyD88 signaling pathway.
doi: 10.1016/j.jep.2021.114063
Figure Lengend Snippet: Fig. 7. In vivo inhibitory effect of FFYH on the inflammatory factors, TNF-α, IL-6, IFN-γ, IP10, and IL-1β caused by influenza a virus (H1N1). The concentration of inflammatory factors in mice sera were quantified with ELISA assays. ##p < 0.05, ###p < 0.01, compared with normal control group; *p < 0.05, **p < 0.01, compared with the virus-infected group (n = 6).
Article Snippet: ELISA kit for examining TNF-α (EK0529),
Techniques: In Vivo, Virus, Concentration Assay, Enzyme-linked Immunosorbent Assay, Control, Infection